My DDU point form notes on cardiac pressure estimation…
The rest of my DDU notes are here.
summary mainly from Bonita Anderson’s “A Sonographer’s Guide to the Assessment of Heart Disease”
Issues in pressure gradient estimation
nonparallel alignment
eg. 20° → cos 20° = 0.94 → 0.942 = 0.88 ∴ 12% underestimation
simplified Bernoulli equation ignores
flow acceleration (underestimates pressures)
issue in prosthetic valves
viscous friction (underestimates pressures)
relevant if CSA < 0.1 cm2 or eccentric wall jets
↑ proximal velocities (V1) (overestimates pressures)
relevant if V1 ≥ 1.2 m/s
eg. aortic stenosis with high output state, significant AR, subvalvular obstruction
wrong Doppler signal
eg. TR instead of MR
arrhythmias
beat to beat variation
average over 2-3 beats (3-5 in AF, whole respiratory cycle for TR)
not same as invasive
can’t estimate peak to peak
in mild-moderate AS, Doppler-derived will be > peak to peak
rapid pressure recovery
causes big discrepancy between pullback gradient and Doppler
Issues in intracardiac pressure estimation
nonparallel alignment and simplified Bernoulli equation issues above under and overestimation
non-simultaneous measurements
eg. RV and LV systole not same time → affects measurements with VSD
BP measurement errors
AS, LVOTO, and sphygmomanometer error
estimation of low pressures by subtraction
eg. LAP = LVSP – 4VMR2
RAP estimation
summarised from Sonographer’s Guide, Bonita, p99
summary
subcostal
IVC size in subcostal, collapse with sniff
PWD of hepatic veins
A4C
tricuspid E/E’
restrictive filling
IVC size and collapsibility
RAP (mmHg) | collapsibility with sniff | |
---|---|---|
(max-min)/max x 100% | ||
0-5 (3) | ≤2.1 | >50% |
5-10 (8) | ≤2.1 | <50% |
5-10 (8) | >2.1 | >50% |
15 | >2.1 | <50% |
in intermediate range (8) can
↓ to 3 if no secondary indices
↑ to high if <35% collapse and secondary indices
stay at 8 if unsure
not valid in ventilated
if IVC ≤ 12mm → RAP < 10 mmHg
young athletes commonly have dilated IVC but normal RAP
→ reassess in left lateral position
secondary indices
hepatic venous Doppler → SFF
PWD (3-5 mm sample volume) in medial hepatic vein
end expiratory apnoea or average 5-7 beats
trace VTIS wave and VTID wave
systolic filling fraction = SFF = VTIS wave / (VTIS wave + VTID wave) x 100
SFF < 55% → RAP > 8mmHg
can also use velocities instead of VTI above
not valid in AF, severe TR
restrictive filling
tricuspid E/E’ > 6
at lateral annulus
→ RAP ≥ 10 mmHg with high sensitivity, specificity
not accurate in ventilated, not valid in AF
RVEDP
same as RAP in absence of tricuspid stenosis – uncommon
if suspicious put CWD through tricuspid inflow and trace inflow VTI to get mean pressure gradient
Pulmonary artery pressures
all require good alignment
PASP
Measure | RSVP = | Issues / assumptions |
---|---|---|
TR jet → peak velocity | 4 VTR2 + RAP | no PS |
modified Bernoulli missing viscous friction terms → underestimates with ↑ blood viscosity or wall jets | ||
VSD jet → peak velocity | SBP – 4VVSD2 | no LVOTO / AS / PS |
SBP error typically 5-10 mmHg | ||
PDA | SBP – 4VPDA2 | SBP error typically 5-10 mmHg |
PAEDP
Measure | PAEDP = | Issues / assumptions |
---|---|---|
PR jet → end diastolic velocity | 4 VPRED2 + RVEDP (RAP) | RVEDP = RAP ie. no TS |
mPAP
Measure | mPAP = | Issues / assumptions |
---|---|---|
PASP and PAEDP | (2 x PAEDP + PASP) / 3 | diastole ~2/3 of cardiac cycle, normal HR |
RVAcT (in ms) | 79-(0.45 x RVAcT) | HR 60-100 bpm |
3-5 mm sample volume just proximal to pulmonary valve in PSAX or RV outflow view | n.b. RVAcT > 120ms → normal PA pressures | |
PR jet → early diastolic peak velocity | 4VPR early diastolic peak2 + RAP | mPAP ≈ pulmonary artery dicrotic notch pressure ≈ this value |
TR jet → VTITR → machine will calculate mean gradient | mean gradient + RAP |
PVR
multiple empiric methods
do not use as substitute for invasive PVR when this value is important to guide therapy
Measure | PVR (WU) = | Issues / assumptions |
---|---|---|
TR jet → Vmax (m/s), RVOT VTI (cm) | (Vmax TR / VTIRVOT) x 10 + 0.16 | can Δ normal vs abnormal PVR (Vmax TR / VTIRVOT > 0.2 → PVR > 2 Wood units) |
Vmax TR is used as surrogate for ΔP – doesn’t account for change in RAP, LAP → underestimates high PVR | ||
RVSP (mmHg), E/E’, RVOT VTI (cm) | (RSVP – E/E’) / VTIRVOT | |
pre-ejection period, total systolic time and acceleration time | see Sonographer’s Guide, p106! | best correlation, chronic heart failure population |
many more… |
other features suggestive of pulmonary hypertension
pulmonary valve
M-mode in PSAX: mid-systolic notching, absent a wave
RVAcT < 100 ms, mid-systolic notching of RV outflow tract flow
↑ PR velocity
RV
dilation, hypertrophy ± moderator band, systolic function
RVPO
↑ TR velocity at time of pulmonary valve opening
RA
dilation of RA, coronary sinus
AV
M-mode: mid systolic notching of AV
commonly also have mitral valve prolapse, pericardial effusions
Left atrial pressures – see diastolic dysfunction notes
Left ventricular diastolic pressure – see diastolic dysfunction notes
Cover image: “Combinpedal” by James Heilman, MD – Own work.
Tags: CVP DDU DDU Notes pulmonary hypertension RAP